Top 5 Lidocaine Creams: Your Relief Guide Now

Ever wish you could just turn down the volume on discomfort? Whether it’s a minor procedure, a tough sunburn, or just general skin sensitivity, that sharp sting can really put a damper on things. Finding relief shouldn’t feel like another chore.

The world of topical numbing creams is surprisingly crowded. You see different strengths, added ingredients, and confusing labels everywhere you look. How do you know which Lidocaine Cream actually works best for *your* specific need? Choosing the wrong one might mean wasting money or, worse, not getting the relief you hoped for.

This post cuts through the noise. We will break down exactly what you need to look for in a Lidocaine Cream—from understanding percentages to spotting helpful extras. By the end, you will feel confident picking the perfect product for your situation.

Let’s dive into how these creams work and how to choose the best one for your comfort.

Top Lidocaine Cream Recommendations

No. 1
HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 2.7 Oz | Unscented Formula | Topical Anesthetic
  • MAXIMUM STRENGTH RELIEF — Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
  • FAST-ACTING LIDOCAINE — Containing 4% lidocaine, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
  • NON-GREASY FORMULA — Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
  • SUPPORT AND INSTRUCTION — Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
  • Compare to Aspercreme with Lidocaine active ingredients
No. 3
WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical Analgesic Cream for Anorectal Itch Relief, Unscented, Child Resistant Packaging 2 oz (60g)
  • Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
  • Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
  • External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
  • How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
  • Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.
No. 4
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz
  • FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb cream with Allantoin, clinically proven to temporarily relieve pain, burning, itching, and discomfort, reduces inflammation and soreness in local and anorectal areas
  • 5% Lidocaine Cream Maximum Strength - This pain relief anti itch cream provides immediate relief for minor aches, minor burns, and minor skin irritations. It also works for postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
  • Enhanced Liposomal Deep Penetrating Skin Numbing Cream - Best efficacy, fast-acting & long-lasting. It begins numbing in 3-5 minutes, peaks after 20-25 minutes, and lasts 1 hour from its peak. Numbing performance may vary depending on the thickness of the skin area and individual metabolism
  • Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply before, during, and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy application and no-mess removal
  • Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing
No. 5
Neosporin + Lidocaine First Aid Triple Antibiotic Ointment, Fast-Acting, Maximum Strength Topical Pain Relief, 24-Hour Infection Protection That Numbs Away The Pain for Minor Wound Care, 0.5 oz
  • .5-ounce tube of Neosporin + Lidocaine First Aid Triple Antibiotic Ointment, by the #1 doctor-recommended brand, has an effective germ-killing formula for 24-hour long-lasting infection protection and fast-acting numbing pain relief for minor wounds
  • Pain relief ointment formulated with triple antibiotic combination of infection-protection ingredients bacitracin zinc, neomycin sulfate and polymyxin B sulfate to help prevent infections in minor cuts, scrapes, and wounds for minor wound care treatment
  • Triple antibiotic ointment also contains fast-acting lidocaine, a topical analgesic that numbs away the pain, for maximum-strength burn pain relief and long-lasting infection protection from painful minor cuts, scrapes, burns, and wounds
  • First aid essential in a compact and portable 0.5-ounce tube, suitable in wound care supplies and first aid kits for home, on-the-go, cars, dorms, travel, camping, and outdoors, provides effective triple antibiotic protection for treatment of minor wounds
  • To use, clean affected area with a BAND-AID Brand Antiseptic Spray and treat with a small amount of first aid topical antibiotic ointment one to three times daily. Cover the minor wound with a BAND-AID Brand Adhesive Bandage for extra protection
No. 6
HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10% Benzyl Alcohol | Topical Anesthetic
  • MAXIMUM STRENGTH RELIEF — Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
  • PAIN RELIEVING LIDOCAINE + BENZYL ALCOHOL — Powerful pain relief ingredients: 4% lidocaine plus 10% benzyl alcohol work together by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
  • NON-GREASY FORMULA — Non-greasy formula goes on smooth; safely apply 3-4 times daily
  • 30-APPLICATIONS PER TUBE — Only a dime size of cream is needed per application to targeted areas for up to 30 applications in each tube
  • SUPPORT AND INSTRUCTION — Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
No. 7
WELMATE 5% Lidocaine Cream for Hemorrhoids, 6 oz Jar – Fast-Acting Lidocaine Numbing Cream & Topical Analgesic Cream for Anorectal Itch Relief
  • Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
  • Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
  • External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
  • How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
  • Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.
No. 8
Aspercreme Essential Oils Lidocaine Pain Relief with No-Mess Roll-On Applicator, Max-Strength Lidocaine Numbs Away Nerve Pain, Moisturizing Aloe Hydrates Skin, Lavender, 2.5 Oz.
  • Contains one (1) 2.5-oz. roll-on bottle of Aspercreme Essential Oils Lidocaine Pain Relief Liquid With No-mess Applicator, Lavender
  • Fast-Acting Relief: Max-strength 4% lidocaine topical numbing liquid targets nerves and numbs away pain
  • No-Mess Application: Convenient roll-on applicator offers targeted relief and keeps hands clean
  • Non-greasy Formula: Aspercreme doesn't leave behind greasy residue or strong odor
  • Maximum-Strength Lidocaine: OTC Aspercreme offers the maximum-strength lidocaine pain relief available without a prescription and is FSA/HSA eligible

Your Essential Guide to Buying Lidocaine Cream

Lidocaine cream helps numb skin. It reduces pain and discomfort. People use it for minor procedures or skin irritations. Choosing the right cream matters for safety and effectiveness. This guide helps you pick the best product.

Key Features to Look For

When you shop for lidocaine cream, check these important things first.

Active Ingredient Strength

Lidocaine strength is key. Most over-the-counter (OTC) creams have lower strengths, often 2% to 5%. Higher strengths (like 10% or more) usually need a doctor’s prescription. Check the label carefully. Stronger doesn’t always mean better for your needs. Match the strength to the pain level you want to treat.

Formulation Type

Lidocaine comes in different forms. Creams are common. Gels spread easily. Sprays offer quick application. Consider how you plan to use the cream. If you need to cover a large area, a cream might work best. For small spots, a spray is fast.

Added Ingredients

Some creams include extra ingredients. Aloe vera or Vitamin E can soothe the skin. Others might have preservatives or fragrances. If you have sensitive skin, look for hypoallergenic or fragrance-free options.

Important Materials and Formulation

The “stuff” inside the tube affects how well the cream works and feels.

Lidocaine Type

Lidocaine itself is the main material. It works by temporarily blocking nerve signals. Ensure the product lists lidocaine clearly as the active ingredient. Some products use related numbing agents, so read the fine print.

Base Ingredients (Excipients)

The base carries the lidocaine to your skin. Common bases include water, oils, or alcohol. Water-based gels absorb quickly. Oil-based creams might stay on the skin longer, providing extended relief. Check the ingredient list for things that might irritate you, like certain alcohols or parabens.

Factors That Improve or Reduce Quality

Not all lidocaine creams perform the same. Quality depends on how they are made and packaged.

Absorption Rate

A good cream absorbs well without leaving a greasy residue. Fast absorption means quicker pain relief. Poorly formulated creams sit on top of the skin. This makes them less effective and messy.

Packaging and Stability

Always buy products in sealed containers. Air and light can break down lidocaine over time, reducing its power. Check the expiration date. Never use expired numbing cream.

Purity and Testing

Reputable brands test their products for purity. While consumer testing is hard to verify, look for brands that follow good manufacturing practices (GMP). High-quality production means you get the strength listed on the label.

User Experience and Use Cases

Think about why you need the cream. This helps you choose the right product for your situation.

Common Use Cases
  • Minor skin procedures (like removing splinters).
  • Temporary relief from bug bites or minor sunburn.
  • Before waxing or shaving sensitive areas.
  • Reducing discomfort from minor medical procedures (check with a doctor first!).
Application Tips

Most creams require you to apply a thin layer to clean, dry skin. You must wait for the cream to work. This waiting time varies, usually 15 to 45 minutes. Do not rub it in too hard. Cover the area with plastic wrap if the instructions suggest it; this helps the cream penetrate better.

Always test a small patch of skin first. This prevents large allergic reactions. If you feel burning or increased irritation, wash it off immediately.


10 Frequently Asked Questions (FAQ) About Lidocaine Cream

Q: How long does lidocaine cream usually take to work?

A: Most creams need 15 to 45 minutes to provide full numbing effects. The exact time depends on the strength and how thick you apply it.

Q: Can I buy lidocaine cream without a prescription?

A: Yes, low-strength lidocaine creams (usually 2% to 5%) are available over the counter (OTC) in most places.

Q: Is lidocaine cream safe for use on broken skin?

A: No. You should never apply lidocaine cream to deep cuts, open wounds, or severely irritated skin unless a doctor tells you to.

Q: What is the maximum safe amount of lidocaine I can use?

A: The safe maximum dose depends on your body weight and the cream strength. Always follow the package directions exactly. When in doubt, ask your pharmacist or doctor.

Q: Will lidocaine cream make me sleepy?

A: When used correctly on the skin, systemic absorption is low. You usually do not feel sleepy. Large amounts applied over huge areas might cause rare side effects.

Q: How long does the numbing effect last?

A: The numbing typically lasts for one to three hours after application, depending on the product and how much was absorbed.

Q: Are there side effects I should watch out for?

A: Common side effects include temporary redness or a mild stinging sensation where you applied it. Serious reactions are rare but include rash or breathing trouble.

Q: Can I use this cream for dental pain relief at home?

A: No. Do not use topical lidocaine creams inside your mouth for toothaches unless specifically directed by a dentist. Oral numbing agents are different.

Q: Does refrigeration improve lidocaine cream quality?

A: No. Store your cream at room temperature, away from direct heat or sunlight. Extreme temperatures can ruin the formula.

Q: If my skin is very dry, will the cream work better or worse?

A: Very dry or cracked skin might absorb the cream faster, which could increase the risk of side effects. Make sure the skin is clean and only slightly moisturized if needed, following product guidelines.